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DeCS
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Descriptor English:
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Axin Signaling Complex
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Descriptor Spanish:
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Complejo de Señalización de la Axina
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Descriptor Portuguese:
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Complexo de Sinalização da Axina
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Synonyms English:
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beta-Catenin Destruction Complex
Destruction Complex, beta-Catenin
Signaling Complex, Axin
beta Catenin Destruction Complex
Axin Signaling Complex Proteins
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Tree Number:
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D05.500.117
D12.776.476.081
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Definition English:
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A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription. |
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History Note English:
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2012
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Allowable Qualifiers English:
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Record Number:
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54555
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Unique Identifier:
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D060465
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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